Journal of Advances in Molecular Biology

Download PDF (600.2 KB) PP. 1 - 8 Pub. Date: March 5, 2019

DOI: 10.22606/jamb.2019.31001

• Pasupuleti Sreenivasa Rao^{*1a
  1a}Research Scientist, Department of Advanced Research Centre, Narayana Medical College
• ^{*1b
  1b}Research Advisory Professor, Narayana College of Pharmacy, Nellore, Andhra Pradesh -524002, India
• Gangapatnam Subramanayam^{2
  2}Director/cardiologist,Department of Cardiology / Department of Advanced Research Centre, Narayana Medical College, Nellore, AP-524002, India
• Perali Ramu Sridhar^{3
  3}Associate Professor, School of Chemistry, University of Hyderabad,Prof. C. R. Rao Road, Gachibowli Hyderabad, 500046, India

Majority of world population up to 80 percent, still relies on traditional medicine. Presently usage of medicinal plant/herbal medicine for treating various disorders and diseases is rapidly growing and they are assumed to have minimal side effects. In ethno traditional medicine Azadirachta indica (Neem) is widely used for centuries. In India, it is extensively used in several native medical practices. Its vegetative parts like leaves, flowers, fruits, seeds and bark are known to possess numerous bioactive compounds, so they are affectionately called as store house of phytochemicals or Village Pharmacy. Its chemical composition is quite complex and few studies effectively characterized and separated few bioactive compounds which has significant biological activities. However, in the current study, we identified, the presence of flavonol galactoside in the neem extracts related to various vegetative parts using LC –MS (Liquid Chromatography and Mass Spectroscopy) spectral analysis. Moreover for the first time, we report the presence of major flavonol galactosides like Quercetin 3-galactoside (C₂₁H₂₀O₁₂) from the vegetative parts of Azadirachta indica collected from Tirumala Hills, Eastern Ghats.

Flavonoids, Quercetin 3-galactoside, Azadirachta indica, Natural products, LC –MS

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